姓名：张春雨
硕士生导师
职称：副教授
联系方式：zhangchunyu@sdfmu.edu.cn
研究方向：
1. 铂类抗肿瘤药物开发及治疗应用;
2. 基于金属团簇药物/探针的纳米生物效应研究;
3. 基于先进光源的单细胞同步辐射成像分析。
主要学术任职：
1. 担任Nano Today, Biomaterials, Journal of Controlled Release等期刊审稿人
主持科研课题：
1. 中国博士后科学基金, 面上项目, 2022M711974, 2022/06-2023/09, 8万元, 已结题, 主持;
2. 永利yl23411官网青年科学基金培育资助计划项目, 202201-003, 2022/10-2024/10, 10万元, 已结题, 主持;
3. 山东省医药卫生科技项目, 青年项目, 202313030397, 2024/01-2025/12, 2万元, 在研, 主持;
4. 永利yl23411官网高层次人才引进经费资助项目, 2023/09-2028/08, 100万, 在研, 主持。
近五年代表性论文（限第一作者和通讯作者）：
(1) Chao Xu, Juanjuan Guo, Qinqin Zheng, Mingchuan Yang, Zhenduo Han, Na Zhang, Chunyu Zhang,* Hongping Chen* and Xiangchun Zhang,* Personalized design enzyme-like activity theanine coated Pt clusters for catalytic damage of bacterial and infection management. Chemical Engineering Journal 2025, 505, 159309.
(2) Chao Xu, Dongfang Xia, Xiangchun Zhang, Qingqiang Yao, Yaling Wang,* Chunyu Zhang,* In situ analysis of metallodrugs at the single-cell level based on synchrotron radiation technology. TrAC-Trends in Analytical Chemistry 2024, 171, 117515.
(3) Chunyu Zhang,* Na Zhang, Wenchao Niu, Ruihan Li, Yanna Liu, Yanling Mu, Chao Xu,* Qingqiang Yao,* Xueyun Gao,* Ultrasmall platinum nanoclusters: A potent chemotherapeutic drug for cancer-specific DNA damage with optimizing therapeutic efficacy while minimizing systemic toxicity. Nano Today 2024, 55, 102195.
(4) Chunyu Zhang, # Kai Zhang,# Yanyan Cui,# Yuecong Guo, Chuan Wang, Chao Xu, Qingqiang Yao, Yuliang Zhao, Chunying Chen,* Yaling Wang,* Multifunctional Nanoprobe for 3D Nanoresolution Imaging of Intact Cell HER2 Protein with Hard X-ray Tomography. Anal. Chem. 2023, 95, 2129-2133. (Cover article)
(5) Chunyu Zhang,# Chao Xu,# Xueyun Gao,* Qingqiang Yao,* Platinum-based Drugs for Cancer Therapy and Anti-tumor Strategies. Theranostics 2022, 12, 2115-2132. (Highly Cited Paper)
(6) Zhesheng He,# Fei Ye,# Chunyu Zhang,# Jiadong Fan,# Zhongying Du, Wencong Zhao, Qing Yuan, Wenchao Niu, Fuping Gao, Bo He, Peng Cao, Lina Zhao, Xuejiao Gao, Xingfa Gao, Bo Sun, Yuhui Dong, Jincun Zhao, Jianxun Qi, Xing-Jie Liang, Huaidong Jiang,* Yong Gong,* Wenjie Tan,* Xueyun Gao,* A Comparison of Remdesivir Versus Gold Cluster in COVID-19 Animal Model: A Better Therapeutic Outcome of Gold Cluster. Nano Today 2022, 44, 101468. (co-first author）
(7) Chunyu Zhang, Shengkun Yao, Chao Xu, Yanan Chang, Yunbing Zong, Kai Zhang, Xiangzhi Zhang, Lijuan Zhang, Chunying Chen, Yuliang Zhao, Huaidong Jiang,* Xueyun Gao,* Yaling Wang,* 3D Imaging and Quantification of the Integrin at a Single-Cell Base on a Multisignal Nanoprobe and Synchrotron Radiation Soft X-ray Tomography Microscopy. Anal. Chem. 2021, 93, 1237-1241.
(8) Chunyu Zhang, Liang Gao,* Qing Yuan, Lina Zhao, Wenchao Niu, Pengju Cai, Jiaojiao Li, Xu Han, Zhesheng He, Fuping Gao, Yaling Wang, Huaidong Jiang, Zhifang Chai, Xueyun Gao,* Is GSH Chelated Pt Molecule Inactive in Anti-Cancer Treatment? A Case Study of Pt6GS4. Small 2020, 16, 2002044.
